梅升辉

姓名：梅升辉 性别：男 职称：副教授

研究方向名称：基于定量药理学和药物基因组学的精准用药研究

电子信箱：

社会任职

1. 北京药理学会第三届临床药理专业委员会委员

2. 北京药学会应用药理专业委员会委员

3. 北京药学会治疗药物监测专业委员会委员

4. 北京药师协会治疗药物监测药师分会委员

5. 中国药理学会定量药理专业委员会第一届临床应用学组委员

个人简历

1. 201108-202509:首都医科大学附属北京天坛医院 任职

2. 200809-201107:首都医科大学 学习

3. 200209-200807:北京大学 学习

重要学术论文

1. Huo Jiping(#), Guo Yangyang(#), Zhang Bo, Zhao Zhigang, Shi Guangzhi(*), Mei Shenghui(*). A UHPLC-MS/MS method for the simultaneous determination of vancomycin, norvancomycin, meropenem, and moxalactam in human plasma and its clinical application.J Mass Spectrom.2023.58(6).e4925.SCI

2. Wei Shifeng(#), Chen Jingcheng(#), Zhao Zhigang(*), Mei Shenghui(*).External validation of population pharmacokinetic models of vancomycin in postoperative neurosurgical patients.Eur J Clin Pharmacol.2023.79(8).1031-1042.SCI

3. Jiang Ruiqi(#), Zhang Dongjie(#), Zhao Zhigang(*), Mei Shenghui(*).Simultaneous determination of 24 antiepileptic drugs and their active metabolites in human plasma by UHPLC-MS/MS.J Pharm Biomed Anal.2023.232.115437.SCI

4. Ruiqi Jiang, Shenghui Mei(*), Zhigang Zhao(*).Leucovorin (folinic acid) rescue for high-dose methotrexate: A review.Journal of Clinical Pharmacy and Therapeutics.2022.47(9).1452-1460.SCI

5. Yang Hua, Zhang Dongjie, Mei Shenghui(*), Zhao Zhigang(*).Simultaneous determination of plasma lamotrigine, lamotrigine N2-glucuronide and lamotrigine N2-oxide by UHPLC-MS/MS in epileptic patients. J Pharm Biomed Anal.2022.220.115017.SCI

6. Jiang Ruiqi, Yang Jiayu, Mei Shenghui(*), Zhao Zhigang(*).Determination of levodopa by chromatography-based methods in biological samples: a review.Anal Sci.2022.38(8).1009-17.SCI

7. Yiming Zhang(#), Liyu Sun(#), Xinwei Chen, Libo Zhao, Xiaoling Wang, Zhigang Zhao(*), Shenghui Mei(*).A Systematic Review of Population Pharmacokinetic Models of Methotrexate.European Journal of Drug Metabolism and Pharmacokinetics.2022.47(2).143-164.SCI

8. Jin Siyao(#), Pang Wenyuan(#), Zhao Libo, Zhao Zhigang, Mei Shenghui(*).Review of HPLC-MS methods for the analysis of nicotine and its active metabolite cotinine in various biological matrices.Biomed Chromatogr.2022.36(6).e5351.SCI

9. Shifeng Wei, Dongjie Zhang, Zhigang Zhao(*), Shenghui Mei(*).Population pharmacokinetic model of vancomycin in postoperative neurosurgical patients.Frontiers in Pharmacology.2022.13.1005791.SCI

10. Qing Zhao(#), Yong Cui(#), Chun Zeng, Xiaohui Ren, Kefu Yu, Song Lin, Zhigang Zhao, Shenghui Mei(*).Association between SNPs and hepatotoxicity in patients with primary central nervous system lymphoma on high-dose methotrexate therapy. Journal of Pharmacy and Pharmacology.2021.73(11).1480-1490.SCI

11. Yiming Zhang(#), Liyu Sun, Libo Zhao, Xiaoling Wang, Zhigang Zhao(*), Shenghui Mei(*).Methotrexate Polyglutamates Analysis by Chromatography Methods in Biological Matrices: A Review.Analytical Sciences.2021.37(12).1655-1664.SCI

12. Mei Shenghui(#), Cui Yong(#), Zhang Dongjie, Zeng Chun, Ren Xiaohui, Yu Kefu, Lin Song(*), Zhao Zhigang(*).Simultaneous determination of urine methotrexate, 7-hydroxy methotrexate, deoxyaminopteroic acid, and 7-hydroxy deoxyaminopteroic acid by UHPLC-MS/MS in patients receiving high-dose methotrexate therapy.Analytical Sciences.2020.36(12).1479-1483.SCI

13. Han Nannan(#)，Jia Lu，Guo Lijia，Su Yingying，Luo Zhenhua，Du Juan，Mei Shenghui(*)，Liu Yi(*).Balanced oral pathogenic bacteria and probiotics promoted wound healing via maintaining mesenchymal stem cell homeostasis.Stem Cell Research & Therapy.2020.11(1).61.SCI

14. Han Jiaqi(#), Mei Shenghui(#), Xu Jiamin, Zhang Dongjie, Jin Siyao, Zhao Zhigang(*), Zhao Libo(*).Simultaneous UPLC-MS/MS Determination of 6-mercaptopurine, 6-methylmercaptopurine and 6-thioguanine in Plasma: Application to the Pharmacokinetic Evaluation of Novel Dosage forms in Beagle Dogs.Current Pharmaceutical Design.2020.26(46).6013-6020.SCI

15. Qing Zhao(#), Siyao Jin(#), Qingyang Liu(#), Zhigang Zhao, Weixing Feng, Shenghui Mei(*).imultaneous Determination of Lamotrigine, Topiramate, Oxcarbazepine, and 10,11-dihydro-10-hydroxycarbazepine in Human Blood Plasma by UHPLC-MS/MS.Current Analytical Chemistry.2020.16(8).1010-1021.SCI

16. Siyao Jin(#), Qing Zhao(#), Dongjie Zhang, Zhigang Zhao, Shenghui Mei(*).Development and validation of an improved HPLC-UV method for simultaneous determination of lamotrigine and oxcarbazepine and its active metabolite 10,11-dihydro-10-hydroxycarbazepine in human blood plasma and comparison with an UHPLC-MS/MS method. Journal of Analytical Science and Technology.2019.10(1).10.SCI

17. Liu Yang(#), Zhang Dongjie(#), Du Juan, Qin Ying, Zhao Zhigang, Shi Yanjun, Mei Shenghui(*), Liu Yi(*).Simultaneous determination of plasma nicotine and cotinine by UHPLC-MS/MS in C57BL/6 mice and its application in a pharmacokinetic study.Biomed Chromatogr.2019.33(10).e4634.SCI

18. Guo Shanshan(#), Mei Shenghui(#), Wang Qiaoyu, Li Xingang, Chen Yang, He Qiyang(*), Zhao Zhigang(*).Determination of cantharidic acid in rat blood by microdialysis combined with UHPLC–MS/MS. International Journal of Mass Spectrometry.2019.440.20-6.SCI